SKU: WP6603 Categories: ,

EHD2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6603-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetEHD2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)60kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human EHD2
SpecificityThis antibody detects endogenous levels of EHD2 at Human, Mouse,Rat
Gene NameEHD2 PAST2
Protein NameEH domain-containing protein 2 (PAST homolog 2)
Other Name
SpeciesHuman
Gene ID30846
UniprotQ9NZN4,
Species.1Mouse
Gene ID.1259300
Uniprot.1Q8BH64,
Species.2Rat
Gene ID.2361512
Uniprot.2Q4V8H8
Cellular LocalizationCell membrane; Peripheral membrane protein; Cytoplasmic side . Membrane, caveola; Peripheral membrane protein; Cytoplasmic side . Endosome membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasm, cytosol . Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes. .
Tissue ExpressionHighly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
Signaling_pathway
Research Areas
FunctionATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes . Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane .
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