Price range: $268.00 through $328.00
Background:
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],
| Size | 50μL/100μL |
| Target | ELOVL5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 28kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ELOVL5. AA range:250-299 |
| Specificity | ELOVL5 Polyclonal Antibody detects endogenous levels of ELOVL5 protein. |
| Gene Name | ELOVL5 |
| Protein Name | Elongation of very long chain fatty acids protein 5 |
| Other Name | ELOVL5; / ELOVL2; / Elongation of very long chain fatty acids protein 5; / 3-keto acyl-CoA synthase ELOVL5; / ELOVL fatty acid elongase 5; / ELOVL FA elongase 5; / Fatty acid elongase 1; / hELO1 |
| Species | Human |
| Gene ID | 60481 |
| Uniprot | Q9NYP7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BHI7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Cell projection, dendrite . In Purkinje cells, the protein localizes to the soma and proximal portion of the dendritic tree. . |
| Tissue Expression | Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. Expressed in the cerebellum. |
| Signaling_pathway | |
| Research Areas | >>Fatty acid elongation; / >>Biosynthesis of unsaturated fatty acids; / >>Metabolic pathways; / >>Fatty acid metabolism |
| Function | Function:May be involved in the elongation of long-chain polyunsaturated fatty acids (PUFAs).,similarity:Belongs to the ELO family.,tissue specificity:Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain., |
