Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ENPP4
Specificity
This antibody detects endogenous levels of ENPP4 at Human, Mouse
Gene Name
ENPP4 KIAA0879 NPP4
Protein Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 4 (E-NPP 4) (NPP-4) (EC 3.1.-.-)
Other Name
Species
Human
Gene ID
22875
Uniprot
Q9Y6X5,
Species.1
Mouse
Gene ID.1
224794
Uniprot.1
Q8BTJ4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell membrane; Single-pass type I membrane protein .
Tissue Expression
Expressed on the surface of vascular endothelia.
Signaling_pathway
Research Areas
Function
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.