SKU: WP7851 Categories: ,

ENPP6 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7851-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetENPP6
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)48kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ENPP6
SpecificityThis antibody detects endogenous levels of ENPP6 at Human, Mouse,Rat
Gene NameENPP6 UNQ1889/PRO4334
Protein NameEctonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form]
Other Name
SpeciesHuman
Gene ID133121
UniprotQ6UWR7,
Species.1Mouse
Gene ID.1320981
Uniprot.1Q8BGN3,
Species.2Rat
Gene ID.2
Uniprot.2B0BND0
Cellular LocalizationCell membrane; Lipid-anchor, GPI-anchor . A small amount of the protein may be found in the extracellular milieu.
Tissue ExpressionPredominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
Signaling_pathway
Research Areas
FunctionCholine-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells . Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity).
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