Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human ENPP6
Specificity
This antibody detects endogenous levels of ENPP6 at Human, Mouse,Rat
Gene Name
ENPP6 UNQ1889/PRO4334
Protein Name
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form]
Other Name
Species
Human
Gene ID
133121
Uniprot
Q6UWR7,
Species.1
Mouse
Gene ID.1
320981
Uniprot.1
Q8BGN3,
Species.2
Rat
Gene ID.2
Uniprot.2
B0BND0
Cellular Localization
Cell membrane; Lipid-anchor, GPI-anchor . A small amount of the protein may be found in the extracellular milieu.
Tissue Expression
Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level).
Signaling_pathway
Research Areas
Function
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells . Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity).