ENPP6 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ENPP6 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 48kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ENPP6 |
| Specificity | This antibody detects endogenous levels of ENPP6 at Human, Mouse,Rat |
| Gene Name | ENPP6 UNQ1889/PRO4334 |
| Protein Name | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form] |
| Other Name | |
| Species | Human |
| Gene ID | 133121 |
| Uniprot | Q6UWR7, |
| Species.1 | Mouse |
| Gene ID.1 | 320981 |
| Uniprot.1 | Q8BGN3, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | B0BND0 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor . A small amount of the protein may be found in the extracellular milieu. |
| Tissue Expression | Predominantly expressed in kidney and brain. In the kidney, expressed specifically in the proximal tubules and thin descending limbs of Henle (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells . Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity). |
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