Product details
Background:
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ENTPD4 rabbit pAb
Ucallm_WP8867-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ENTPD4 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 68kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ENTPD4 |
| Specificity | This antibody detects endogenous levels of ENTPD4 at Human, Mouse |
| Gene Name | ENTPD4 KIAA0392 LALP70 LYSAL1 |
| Protein Name | Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase) |
| Other Name | |
| Species | Human |
| Gene ID | 9583 |
| Uniprot | Q9Y227, |
| Species.1 | Mouse |
| Gene ID.1 | 100862375 |
| Uniprot.1 | Q9DBT4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein . Lysosome membrane; Multi-pass membrane protein.; [Isoform 2]: Golgi apparatus membrane; Multi-pass membrane protein . |
| Tissue Expression | Ubiquitous. Highest expression in testis and lowest in bladder. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome |
| Research Areas | |
| Function | [Isoform 1]: Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner, with a preference for pyrimidines. Preferentially hydrolyzes UTP and TTP. AMP, ADP, ATP and UMP are not substrates . Preferentially activated by Ca(2+) over Mg(2+) .; [Isoform 2]: Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca(2+) or Mg(2+) equally. |
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