This gene encodes a large coiled coil domain-containing protein that functions in autophagy during starvation conditions. Mutations in this gene cause Vici syndrome. [provided by RefSeq, Aug 2015],
Specifications
Size
50μL/100μL
Target
EPG5
Reactivity
Human, Mouse
Applications
WB, IHC, IF
MW(Calculated)
292kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:1000-2000; IHC 1:200-500; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthetic peptide from human protein at AA range: 141-190
Specificity
The antibody detects endogenous EPG5
Gene Name
EPG5 KIAA1632
Protein Name
Ectopic P granules protein 5 homolog
Other Name
Ectopic P granules protein 5 homolog
Species
Human
Gene ID
57724
Uniprot
Q9HCE0,
Species.1
Mouse
Gene ID.1
100502841
Uniprot.1
Q80TA9
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, perinuclear region . Lysosome .
Tissue Expression
Brain,Cervix,Lymph node,Placenta,
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal
Research Areas
Function
sequence Caution:Translated as Trp.,similarity:Belongs to the UPF0493 family.,