Name: EPPI rabbit pAb
SKU: WP3822
Price: 268 USD
Availability: InStock

EPPI rabbit pAb

Ucallm_WP3822-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP3822-100

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Product details

Background:

This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],

Specifications

Size	50μL/100μL
Target	EPPI
Reactivity	Human, Mouse, Rat
Applications	WB
MW(Calculated)	15kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human EPPI AA range: 55-105
Specificity	This antibody detects endogenous levels of EPPI at Human/Mouse/Rat
Gene Name	EPPIN SPINLW1 WAP7 WFDC7
Protein Name	EPPI
Other Name
Species	Human
Gene ID	100526773
Uniprot	O95925,
Species.1	Mouse
Gene ID.1	75526
Uniprot.1	Q9DA01,
Species.2	Rat
Gene ID.2	685161
Uniprot.2	D4A2Z2
Cellular Localization	[Isoform 1]: Secreted. Cell surface. Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
Tissue Expression	In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells.
Signaling_pathway
Research Areas
Function	similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 1 WAP domain.,tissue specificity:Expressed in epididymis and testis.,tissue specificity:Ubiquitously expressed, but the highest levels are found in epididymis, testis and trachea.,