SKU: WP15650 Categories: ,

Epigen Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15650-100
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Product details

Background:

The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Specifications

Size50μL/100μL
TargetEpigen
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)17kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human EPGN. AA range:11-60
SpecificityEpigen Polyclonal Antibody detects endogenous levels of Epigen protein.
Gene NameEPGN
Protein NameEpigen
Other NameEPGN; / Epigen; / Epithelial mitogen; / EPG
SpeciesHuman
Gene ID255324
UniprotQ6UW88,
Species.1Mouse
Gene ID.171920
Uniprot.1Q924X1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Membrane; Single-pass type I membrane protein .; [Isoform 2]: Membrane; Single-pass type I membrane protein .; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 5]: Secreted .; [Isoform 6]: Secreted .
Tissue Expression
Signaling_pathway
Research Areas
FunctionFunction:Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.,similarity:Contains 1 EGF-like domain.,
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