EPSTI1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | EPSTI1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EPSTI1 |
| Specificity | This antibody detects endogenous levels of EPSTI1 at Human, Mouse,Rat |
| Gene Name | EPSTI1 |
| Protein Name | Epithelial-stromal interaction protein 1 |
| Other Name | |
| Species | Human |
| Gene ID | 94240 |
| Uniprot | Q96J88, |
| Species.1 | Mouse |
| Gene ID.1 | 108670 |
| Uniprot.1 | Q8VDI1, |
| Species.2 | Rat |
| Gene ID.2 | 498547 |
| Uniprot.2 | Q5BK43 |
| Cellular Localization | |
| Tissue Expression | Highly expressed in placenta, small intestine, spleen, kidney, thymus, liver, salivary gland and testes. Weakly expressed in breast, skeletal muscle and colon. Highly expressed in breast cancer upon interaction between tumor cells and stromal cells in vitro. Expressed in blood mononuclear cells from patients with systemic lupus erythematosus (SLE). |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (By similarity). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (By similarity). |
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