Price range: $268.00 through $328.00
Background:
epiphycan(EPYC) Homo sapiens Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | EPYC |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 35kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 140-220 |
| Specificity | EPYC Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | EPYC DSPG3 PGLB SLRR3B |
| Protein Name | Epiphycan (Dermatan sulfate proteoglycan 3) (Proteoglycan-Lb) (PG-Lb) (Small chondroitin/dermatan sulfate proteoglycan) |
| Other Name | |
| Species | Human |
| Gene ID | 1833 |
| Uniprot | Q99645, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P70186 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted, extracellular space, extracellular matrix . |
| Tissue Expression | Cartilage, ligament, and placenta. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.,PTM:The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class III subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Cartilage, ligament, and placenta., |
