Price range: $268.00 through $328.00
Background:
function:May play a role as calcium-regulated intrinsic membrane protein., similarity:Belongs to the extended synaptotagmin family., similarity:Contains 5 C2 domains., subcellular location:Localizes to intracellular membranes., tissue specificity:Widely expressed.,
| Size | 50μL/100μL |
| Target | ESYT1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 121kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ESYT1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ESYT1 FAM62A KIAA0747 MBC2 |
| Protein Name | Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) |
| Other Name | |
| Species | Human |
| Gene ID | 23344 |
| Uniprot | Q9BSJ8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q3U7R1, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q9Z1X1 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Cell membrane; Peripheral membrane protein . Localizes primarily to the endoplasmic reticulum (PubMed:29469807). Recruited to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels (PubMed:29469807, PubMed:22250200). . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May play a role as calcium-regulated intrinsic membrane protein.,similarity:Belongs to the extended synaptotagmin family.,similarity:Contains 5 C2 domains.,subcellular location:Localizes to intracellular membranes.,tissue specificity:Widely expressed., |
