SKU: WP12256 Categories: ,

ETL Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12256-100
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Product details

Background:

developmental stage:Up-regulated in the adult heart., domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation., function:Could be involved in cardiac development., PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit., similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily., similarity:Contains 1 GPS domain., similarity:Contains 2 EGF-like domains., subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface., tissue specificity:Mainly expressed in smooth muscle.,

Specifications

Size50μL/100μL
TargetETL
ReactivityHuman, Mouse, Rat
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)77kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ELTD1. AA range:251-300
SpecificityETL Polyclonal Antibody detects endogenous levels of ETL protein.
Gene NameELTD1
Protein NameEGF latrophilin and seven transmembrane domain-containing protein 1
Other NameELTD1; / ETL; / EGF; / latrophilin and seven transmembrane domain-containing protein 1; / EGF-TM7-latrophilin-related protein; / ETL protein
SpeciesHuman
Gene ID64123
UniprotQ9HBW9,
Species.1Mouse
Gene ID.1
Uniprot.1Q923X1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Multi-pass membrane protein .
Tissue ExpressionDetected in the majority of epithelial cells in tumor and normal tissues. Expressed also in human umbilical vein endothelial cells.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Up-regulated in the adult heart.,Domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation.,Function:Could be involved in cardiac development.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 2 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface.,tissue specificity:Mainly expressed in smooth muscle.,
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