Product details
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FATP2 rabbit pAb
Ucallm_WP6060-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SLC27A2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 68kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FATP2 |
| Specificity | This antibody detects endogenous levels of FATP2 at Human, Mouse,Rat |
| Gene Name | SLC27A2 ACSVL1 FACVL1 FATP2 VLACS |
| Protein Name | Very long-chain acyl-CoA synthetase (VLACS) (VLCS) (Fatty acid transport protein 2) (FATP-2) (Fatty-acid-coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (Solute carrier family 27 member 2) (THCA-CoA ligase) (Very long-chain-fatty-acid-CoA ligase) |
| Other Name | |
| Species | Human |
| Gene ID | 11001 |
| Uniprot | O14975, |
| Species.1 | Mouse |
| Gene ID.1 | 26458 |
| Uniprot.1 | O35488, |
| Species.2 | Rat |
| Gene ID.2 | 65192 |
| Uniprot.2 | P97524 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . Peroxisome membrane; Peripheral membrane protein . Cell membrane; Multi-pass membrane protein . Microsome . |
| Tissue Expression | Expressed in liver, kidney, placenta and pancreas. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Peroxisome;Organismal Systems >> Endocrine system >> PPAR signaling pathway |
| Research Areas | |
| Function | Acyl CoA synthetase that activates long-chain and very long-chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl-CoA . Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid . Does not activate C24 bile acids, cholate and chenodeoxycholate . In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol . Exhibits long-chain fatty acids (LCFA) transport activity and plays an important role in hepatic fatty acid uptake .; [Isoform 1]: Exhibits both long-chain fatty acids (LCFA) transport activity and acyl CoA synthetase towards very long-chain fatty acids . Shows a preference for generating CoA derivatives of n-3 fatty acids, which are preferentially trafficked into phosphatidylinositol .; [Isoform 2]: Exhibits long-chain fatty acids (LCFA) transport activity but lacks acyl CoA synthetase towards very long-chain fatty acids. |
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