Price range: $268.00 through $328.00
Background:
This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011],
| Size | 50μL/100μL |
| Target | FDC-SP |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 10kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from the C-terminal region of human FDC-SP. AA range: 26-75 |
| Specificity | FDC-SP Polyclonal Antibody detects endogenous levels of FDC-SP protein. |
| Gene Name | FDCSP |
| Protein Name | Follicular dendritic cell secreted peptide |
| Other Name | FDCSP; / C4orf7; / Follicular dendritic cell secreted peptide; / FDC secreted protein; / FDC-SP |
| Species | Human |
| Gene ID | 260436 |
| Uniprot | Q8NFU4 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted. |
| Tissue Expression | Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Can bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.,tissue specificity:Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon., |
