FLAP rabbit pAb
Ucallm_WP9024-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ALOX5AP |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 18kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FLAP |
| Specificity | This antibody detects endogenous levels of FLAP at Human, Mouse,Rat |
| Gene Name | ALOX5AP FLAP |
| Protein Name | Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein) |
| Other Name | |
| Species | Human |
| Gene ID | 241 |
| Uniprot | P20292, |
| Species.1 | Mouse |
| Gene ID.1 | 11690 |
| Uniprot.1 | P30355, |
| Species.2 | Rat |
| Gene ID.2 | 29624 |
| Uniprot.2 | P20291 |
| Cellular Localization | Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway |
| Research Areas | |
| Function | Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. |
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