SKU: WP2386 Categories: ,

FLIP1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2386-100
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Product details

Background:

function:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A., similarity:Belongs to the FILIP1 family., subunit:Interacts with FLNA., tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.,

Specifications

Size50μL/100μL
TargetFLIP1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)133kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityFLIP1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameFILIP1 KIAA1275
Protein NameFilamin-A-interacting protein 1 (FILIP)
Other Name
SpeciesHuman
Gene ID27145
UniprotQ7Z7B0,
Species.1Mouse
Gene ID.1
Uniprot.1Q9CS72,
Species.2Rat
Gene ID.2
Uniprot.2Q8K4T4
Cellular LocalizationCytoplasm, cytoskeleton .
Tissue ExpressionModerately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.
Signaling_pathway
Research Areas
FunctionFunction:By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.,similarity:Belongs to the FILIP1 family.,subunit:Interacts with FLNA.,tissue specificity:Moderately expressed in adult heart and brain. Weakly expressed in lung, skeletal muscle, ovary, testis, kidney, and fetal brain, and hardly detectable in liver, pancreas, spleen, and fetal liver. Within brain, moderate expression is found in amygdala and caudate nucleus.,
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