Product details
Background:
- Please choose product options by visiting U-Blot® Human CD303/CLEC4C Antibody (122A2), FITC.
- Please choose product options by visiting U-Blot® APLP2 Polyclonal Antibody.
- Please choose product options by visiting U-Blot® Human vWF Antibody (12A2H1).
- Please choose product options by visiting FMO4 rabbit pAb.
- Please choose product options by visiting MPEG1 rabbit pAb.
FMO5 rabbit pAb
Ucallm_WP6747-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FMO5 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 59kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FMO5 |
| Specificity | This antibody detects endogenous levels of FMO5 at Human, Mouse,Rat |
| Gene Name | FMO5 |
| Protein Name | Dimethylaniline monooxygenase [N-oxide-forming] 5 (Dimethylaniline oxidase 5) (Hepatic flavin-containing monooxygenase 5) (FMO 5) |
| Other Name | |
| Species | Human |
| Gene ID | 2330 |
| Uniprot | P49326, |
| Species.1 | Mouse |
| Gene ID.1 | 14263 |
| Uniprot.1 | P97872, |
| Species.2 | Rat |
| Gene ID.2 | 246248 |
| Uniprot.2 | Q8K4C0 |
| Cellular Localization | Microsome membrane . Endoplasmic reticulum membrane. |
| Tissue Expression | Expressed in fetal and adult liver. |
| Signaling_pathway | |
| Research Areas | |
| Function | Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters . Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive . In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable) . Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline . Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity . Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects (By similarity). |
Please login to post questions
Related products
