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FMT rabbit pAb
Ucallm_WP17240-50
Price range: $268.00 through $328.00
Product details
Background:
The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011],
Specifications
| Size | 50μL/100μL |
| Target | FMT |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 43kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FMT AA range: 115-165 |
| Specificity | This antibody detects endogenous levels of FMT at Human/Mouse/Rat |
| Gene Name | MTFMT FMT FMT1 |
| Protein Name | FMT |
| Other Name | |
| Species | Human |
| Gene ID | 123263 |
| Uniprot | Q96DP5, |
| Species.1 | Mouse |
| Gene ID.1 | 69606 |
| Uniprot.1 | Q9D799, |
| Species.2 | Rat |
| Gene ID.2 | 315763 |
| Uniprot.2 | Q5I0C5 |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>One carbon pool by folate; / >>Aminoacyl-tRNA biosynthesis; / >>Metabolic pathways |
| Function | Catalytic activity:10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).,Domain:Composed of an N- and a C-terminal domain. The N-terminal domain carries the tetrahydrofolate (THF)-binding site and the C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction.,Function:Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.,similarity:Belongs to the fmt family., |
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