SKU: WP7274 Categories: ,

FNTA rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7274-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetFNTA
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)42kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human FNTA
SpecificityThis antibody detects endogenous levels of FNTA at Human, Mouse,Rat
Gene NameFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)
Other Name
SpeciesHuman
Gene ID2339
UniprotP49354,
Species.1Mouse
Gene ID.114272
Uniprot.1Q61239,
Species.2Rat
Gene ID.225318
Uniprot.2Q04631
Cellular Localization
Tissue Expression
Signaling_pathway
Research Areas
FunctionEssential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
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