Name: U-Blot® FoxA2 Rabbit mAb
SKU: WR4938
Price: 268 USD
Availability: InStock

U-Blot® FoxA2 Rabbit mAb

Ucallm_WR4938-50

Price range: $268.00 through $328.00

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SKU: WR4938-50

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Product details

Background:This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008],

Specifications

Size	50μL/100μL
Target	FoxA2
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	48kD
MW(Observed)	50kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:100-1:500; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1161R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	FOXA2
Protein Name	Hepatocyte nuclear factor 3-beta
Other Name	FOXA2; / HNF3B; / TCF3B; / Hepatocyte nuclear factor 3-beta; / HNF-3-beta; / HNF-3B; / Forkhead box protein A2; / Transcription factor 3B; / TCF-3B
Species	Human
Gene ID	3170
Uniprot	Q9Y261,
Species.1	Mouse
Gene ID.1
Uniprot.1	P35583
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner; in response to insulin signaling via AKT1 is exported from the nucleus.
Tissue Expression	Liver,Lung,
Signaling_pathway	Organismal Systems >> Aging >> Longevity regulating pathway - multiple species
Research Areas	>>Longevity regulating pathway - multiple species; / >>Maturity onset diabetes of the young
Function	Function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Binds TLE1.,