FTβ Polyclonal Antibody
Ucallm_WP12377-50
Price range: $268.00 through $328.00
Product details
Background:
catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate., cofactor:Binds 1 zinc ion per subunit., function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding., similarity:Belongs to the protein prenyltransferase subunit beta family., similarity:Contains 5 PFTB repeats., subunit:Heterodimer of an alpha and a beta subunit.,
Specifications
| Size | 50μL/100μL |
| Target | FTβ |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FNTB. AA range:255-304 |
| Specificity | FTβ Polyclonal Antibody detects endogenous levels of FTβ protein. |
| Gene Name | FNTB |
| Protein Name | Protein farnesyltransferase subunit beta |
| Other Name | FNTB; / Protein farnesyltransferase subunit beta; / FTase-beta; / CAAX farnesyltransferase subunit beta; / Ras proteins prenyltransferase subunit beta |
| Species | Human |
| Gene ID | 2342 |
| Uniprot | P49356, |
| Species.1 | Mouse |
| Gene ID.1 | 110606 |
| Uniprot.1 | Q8K2I1, |
| Species.2 | Rat |
| Gene ID.2 | 64511 |
| Uniprot.2 | Q02293 |
| Cellular Localization | cytosol,microtubule associated complex,protein farnesyltransferase complex, |
| Tissue Expression | Neuroblastoma,Placenta,Retina, |
| Signaling_pathway | |
| Research Areas | >>Terpenoid backbone biosynthesis |
| Function | Catalytic activity:Farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.,cofactor:Binds 1 zinc ion per subunit.,Function:Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.,similarity:Belongs to the protein prenyltransferase subunit beta family.,similarity:Contains 5 PFTB repeats.,subunit:Heterodimer of an alpha and a beta subunit., |
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