Product details
Background:
FUT10 rabbit pAb
Ucallm_WP7058-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | FUT10 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 53kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human FUT10 |
| Specificity | This antibody detects endogenous levels of FUT10 at Human, Mouse,Rat |
| Gene Name | FUT10 |
| Protein Name | Alpha-(1,3)-fucosyltransferase 10 (Fucosyltransferase X) (Fuc-TX) (FucT-X) (Galactoside 3-L-fucosyltransferase 10) (Fucosyltransferase 10) |
| Other Name | |
| Species | Human |
| Gene ID | 84750 |
| Uniprot | Q6P4F1, |
| Species.1 | Mouse |
| Gene ID.1 | 171167 |
| Uniprot.1 | Q5F2L2, |
| Species.2 | Rat |
| Gene ID.2 | 497619 |
| Uniprot.2 | Q5F2L1 |
| Cellular Localization | [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein . Golgi apparatus membrane; Single-pass type II membrane protein .; [Isoform 4]: Golgi apparatus . Lysosome .; [Isoform 5]: Endoplasmic reticulum membrane; Single-pass type II membrane protein . Golgi apparatus membrane; Single-pass type II membrane protein . |
| Tissue Expression | Expressed in lung, digestive tract, gall bladder, placenta, kidney, uterus and brain. Not detected in spleen, heart, muscle, liver and pancreas. |
| Signaling_pathway | |
| Research Areas | |
| Function | Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors. Postulated to generate core alpha(1->3)-fucose epitope within the chitobiose unit of biantennary N-glycans, providing for a recognition signal to reorient aberrantly folded glycoproteins for degradation . Involved in biosynthesis of Lewis X-carrying biantennary N-glycans that regulate neuron stem cell self-renewal during brain development (By similarity).; [Isoform 1]: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit.; [Isoform 4]: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit.; [Isoform 5]: Catalyzes the transfer of fucosyl moiety from GDP-beta-L-fucose to the innermost GlcNAc residue in biantennary N-glycan acceptors. Does not fucosylate GlcNAc within type 2 lactosamine unit. |
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