Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | FXR2 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 74kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FXR2. AA range:551-600 |
| Specificity | FXR2 Polyclonal Antibody detects endogenous levels of FXR2 protein. |
| Gene Name | FXR2 |
| Protein Name | Fragile X mental retardation syndrome-related protein 2 |
| Other Name | FXR2; / FMR1L2; / Fragile X mental retardation syndrome-related protein 2 |
| Species | Human |
| Gene ID | 9513 |
| Uniprot | P51116, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9WVR4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm. |
| Tissue Expression | Brain,Epithelium,Lymph,PNS,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:RNA-binding protein.,similarity:Belongs to the FMR1 family.,similarity:Contains 2 KH domains.,subunit:Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3., |
