SKU: WP6512 Categories: ,

GALNT3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6512-100
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Product details

Background:

Specifications

TargetGALNT3
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)70kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human GALNT3
Sequence
SpecificityThis antibody detects endogenous levels of GALNT3 at Human, Mouse
Gene NameGALNT3
Protein NamePolypeptide N-acetylgalactosaminyltransferase 3 (Polypeptide GalNAc transferase 3) (GalNAc-T3) (pp-GaNTase 3) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3)
Other Name
SpeciesHuman
Gene ID-12591
UniprotQ14435,
Species.1Mouse
Gene ID-214425
Uniprot.1P70419
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein . Resides preferentially in the trans and medial parts of the Golgi stack.
Tissue ExpressionExpressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney.
Signaling_pathway
Research Areas
FunctionCatalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. Plays a central role in phosphate homeostasis.
RRID
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