Price range: $268.00 through $328.00
Background:
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013],
| Size | 50μL/100μL |
| Target | GBP2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 65kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 160-240 |
| Specificity | GBP2 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | GBP2 |
| Protein Name | Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) |
| Other Name | |
| Species | Human |
| Gene ID | 2634 |
| Uniprot | P32456, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9Z0E6, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q63663 |
| Cellular Localization | Cytoplasm . Cytoplasm, perinuclear region . Golgi apparatus membrane . Membrane; Lipid-anchor . Cytoplasmic vesicle . GBP2-GBP5 dimers localize to the Golgi apparatus. . |
| Tissue Expression | Foreskin,Lung,Skin,Spinal cord,Thymus, |
| Signaling_pathway | Organismal Systems >> Immune system >> NOD-like receptor signaling pathway |
| Research Areas | >>NOD-like receptor signaling pathway |
| Function | Function:Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product.,induction:By interferon gamma during macrophage activation.,similarity:Belongs to the GBP family., |
