Price range: $268.00 through $328.00
Background:
This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008],
| Target | GCM1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 48kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human GCM1 AA range: 298-348 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of GCM1 at Human/Mouse/Rat |
| Gene Name | GCM1 GCMA |
| Protein Name | GCM1 |
| Other Name | |
| Species | Human |
| Gene ID-1 | 8521 |
| Uniprot | Q9NP62, |
| Species.1 | Mouse |
| Gene ID-2 | 14531 |
| Uniprot.1 | P70348, |
| Species.2 | Rat |
| Gene ID-3 | 29394 |
| Uniprot.2 | Q9Z288 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008], |
| Cellular Localization | Nucleus . |
| Tissue Expression | Highly expressed in the placenta (PubMed:10542267). Expressed in trophoblast cells of the villi (PubMed:27917469). |
| Signaling_pathway | |
| Research Areas | >>Parathyroid hormone synthesis, secretion and action |
| Function | Function:Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer.,similarity:Contains 1 GCM DNA-binding domain.,tissue specificity:Placenta specific., |
| RRID |
