SKU: WP0845 Categories: ,

ARF5 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0845-100
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Product details

Background:

ADP ribosylation factor 5(ARF5) Homo sapiens This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010],

Specifications

TargetARF5
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)19kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 40-120
Sequence
SpecificityARF5 Polyclonal Antibody detects endogenous levels of protein.
Gene NameARF5
Protein NameADP-ribosylation factor 5
Other Name
SpeciesHuman
Gene ID-1381
UniprotP84085,
Species.1Mouse
Gene ID-2
Uniprot.1P84084,
Species.2Rat
Gene ID-3
Uniprot.2P84083
Organism-4
Gene ID-4
SwissProt-4
BackgroundADP ribosylation factor 5(ARF5) Homo sapiens This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010],
Cellular LocalizationGolgi apparatus . Cytoplasm, perinuclear region . Membrane; Lipid-anchor . Golgi apparatus, trans-Golgi network membrane; Lipid-anchor .
Tissue ExpressionBrain,Lung,Skin,Tongue,
Signaling_pathway
Research Areas>>Endocytosis
FunctionFunction:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.,similarity:Belongs to the small GTPase superfamily.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Binds ASAP2.,
RRID
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