Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human GKAP1
Specificity
This antibody detects endogenous levels of GKAP1 at Human, Mouse,Rat
Gene Name
GKAP1 GKAP42 FKSG21
Protein Name
G kinase-anchoring protein 1 (cGMP-dependent protein kinase-anchoring protein of 42 kDa)
Other Name
Species
Human
Gene ID
80318
Uniprot
Q5VSY0,
Species.1
Mouse
Gene ID.1
56278
Uniprot.1
Q9JMB0,
Species.2
Rat
Gene ID.2
361202
Uniprot.2
Q5XIG5
Cellular Localization
Golgi apparatus .
Tissue Expression
Signaling_pathway
Research Areas
Function
Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation.