SKU: WP7871 Categories: ,

GNB4 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7871-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetGNB4
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)37kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human GNB4
SpecificityThis antibody detects endogenous levels of GNB4 at Human, Mouse,Rat
Gene NameGNB4
Protein NameGuanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Other Name
SpeciesHuman
Gene ID59345
UniprotQ9HAV0,
Species.1Mouse
Gene ID.114696
Uniprot.1P29387,
Species.2Rat
Gene ID.2294962
Uniprot.2O35353
Cellular Localization
Tissue ExpressionStrongly expressed in lung and placenta, whereas it is weakly expressed in brain and heart. Abundantly expressed in the axons and Schwann cells of peripheral nerves.
Signaling_pathwayOrganismal Systems >> Immune system >> Chemokine signaling pathway;Organismal Systems >> Endocrine system >> Relaxin signaling pathway;Organismal Systems >> Nervous system >> Glutamatergic synapse;Organismal Systems >> Nervous system >> Cholinergic synapse;Organismal Systems >> Nervous system >> Dopaminergic synapse;Human Diseases >> Cancer: overview >> Pathways in cancer;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Research Areas
FunctionGuanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
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