Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human GLDC
Specificity
This antibody detects endogenous levels of GLDC at Human, Mouse
Gene Name
GLDC GCSP
Protein Name
Glycine dehydrogenase [decarboxylating], mitochondrial (Glycine cleavage system P protein) (Glycine decarboxylase)
Other Name
Species
Human
Gene ID
2731
Uniprot
P23378,
Species.1
Mouse
Gene ID.1
104174
Uniprot.1
Q91W43
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Mitochondrion .
Tissue Expression
Signaling_pathway
Research Areas
Function
The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH).