Price range: $268.00 through $328.00
Background:
function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., similarity:Belongs to the G-alpha family. G(12) subfamily., subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5.,
| Size | 50μL/100μL |
| Target | GNA12 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 41kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | GNA12 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | GNA12 |
| Protein Name | Guanine nucleotide-binding protein subunit alpha-12 (G alpha-12) (G-protein subunit alpha-12) |
| Other Name | |
| Species | Human |
| Gene ID | 2768 |
| Uniprot | Q03113, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P27600, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q63210 |
| Cellular Localization | Cell membrane; Lipid-anchor . Lateral cell membrane; Lipid-anchor . Cytoplasm . CDH1 enhances cell membrane localization. . |
| Tissue Expression | Brain,Pancreas,Placenta,Uterus, |
| Signaling_pathway | Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton;Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction;Human Diseases >> Cancer: overview >> Pathways in cancer;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway;Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway;Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway;Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway |
| Research Areas | >>MAPK signaling pathway; / >>cGMP-PKG signaling pathway; / >>Sphingolipid signaling pathway; / >>Phospholipase D signaling pathway; / >>Vascular smooth muscle contraction; / >>Long-term depression; / >>Regulation of actin cytoskeleton; / >>Parathyroid hormone synthesis, secretion and action; / >>Pathogenic Escherichia coli infection; / >>Human cytomegalovirus infection; / >>Pathways in cancer |
| Function | Function:Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.,similarity:Belongs to the G-alpha family. G(12) subfamily.,subunit:G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts with UBXD5., |
