Price range: $268.00 through $328.00
Background:
The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | GNL1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 69kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNL1. AA range:61-110 |
| Specificity | GNL1 Polyclonal Antibody detects endogenous levels of GNL1 protein. |
| Gene Name | GNL1 |
| Protein Name | Guanine nucleotide-binding protein-like 1 |
| Other Name | GNL1; / HSR1; / Guanine nucleotide-binding protein-like 1; / GTP-binding protein HSR1 |
| Species | Human |
| Gene ID | 2794 |
| Uniprot | P36915, |
| Species.1 | Mouse |
| Gene ID.1 | 14670 |
| Uniprot.1 | P36916, |
| Species.2 | Rat |
| Gene ID.2 | 309593 |
| Uniprot.2 | Q6MG06 |
| Cellular Localization | extracellular space,nucleus, |
| Tissue Expression | Cervix,Muscle,Peripheral blood leukocyte,Skin,T-cell, |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,Function:Possible regulatory or functional link with the histocompatibility cluster.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family., |
