Price range: $268.00 through $328.00
Background:
The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],
| Size | 50μL/100μL |
| Target | GNL3L |
| Reactivity | Human, Rat, Mouse, Cat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 66kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GNL3L. AA range:71-120 |
| Specificity | GNL3L Polyclonal Antibody detects endogenous levels of GNL3L protein. |
| Gene Name | GNL3L |
| Protein Name | Guanine nucleotide-binding protein-like 3-like protein |
| Other Name | GNL3L; / Guanine nucleotide-binding protein-like 3-like protein |
| Species | Human |
| Gene ID | 54552 |
| Uniprot | Q9NVN8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6PGG6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus, nucleolus . |
| Tissue Expression | Lung,Skin, |
| Signaling_pathway | |
| Research Areas | >>Ribosome biogenesis in eukaryotes |
| Function | Domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,Function:Required for normal processing of ribosomal pre-rRNA. Required for cell proliferation. Binds GTP.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family., |
