Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human GNMT
Specificity
This antibody detects endogenous levels of GNMT at Human, Mouse,Rat
Gene Name
GNMT
Protein Name
Glycine N-methyltransferase (EC 2.1.1.20)
Other Name
Species
Human
Gene ID
27232
Uniprot
Q14749,
Species.1
Mouse
Gene ID.1
14711
Uniprot.1
Q9QXF8,
Species.2
Rat
Gene ID.2
25134
Uniprot.2
P13255
Cellular Localization
Cytoplasm .
Tissue Expression
Expressed only in liver, pancreas, and prostate.
Signaling_pathway
Research Areas
Function
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate. Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.