Price range: $268.00 through $328.00
Background:
function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II., PTM:Phosphorylated., similarity:Contains 2 BSD domains., subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60.,
| Size | 50μL/100μL |
| Target | TFIIH p62 |
| Reactivity | Human |
| Applications | WB, IP, ICC |
| MW(Calculated) | |
| MW(Observed) | 62kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:300; ICC 1:50 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 16E10 |
| Immunogen | Purified recombinant human GTF2H1protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of GTF2H1 and does not cross-react with related proteins. |
| Gene Name | gtf2h1 |
| Protein Name | |
| Other Name | Basic transcription factor 2 62 kDa subunit; / Basic transcription factor 62 kDa subunit; / BTF 2; / BTF2; / BTF2 p62; / General transcription factor IIH polypeptide 1; / General transcription factor IIH subunit 1; / General transcription factor IIH, polypeptide 1, 62kDa; / gtf2h1; / TF2H1; / TF2H1_HUMAN; / TFB1; / TFIIH; / TFIIH basal transcription factor complex p62 subunit. |
| Species | Human |
| Gene ID | 2965 |
| Uniprot | P32780, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9DBA9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Liver,Lung, |
| Signaling_pathway | |
| Research Areas | >>Basal transcription factors; / >>Nucleotide excision repair; / >>Viral carcinogenesis |
| Function | Function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,PTM:Phosphorylated.,similarity:Contains 2 BSD domains.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with PUF60., |
