U-Blot® Histone H2A (Acetyl Lys119) Rabbit pAb

Price range: $288.00 through $368.00

SKU: WP0380-100
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Product details

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],

Specifications

TargetHistone H2A
ReactivityHuman,Mouse,Rat
ApplicationWB,ELISA
MW(Calculated)
MW(Observed)15kD
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationAcetyl
Modification siteLys119
Recommended dilution ratioWB 1:1000-2000;ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human Histone H2A (Acetyl Lys119)
Sequence
SpecificityThis antibody detects endogenous levels of Human,Mouse,Rat Histone H2A (Acetyl Lys119)
Gene nameHIST1H2AG H2AFP; HIST1H2AI H2AFC; HIST1H2AK H2AFD; HIST1H2AL H2AFI; HIST1H2AM H2AFN
Protein nameHistone H2A (Acetyl Lys119)
Alternative nameHistone H2A type 1;H2A.1;Histone H2A/p;
Organism-1Human
Gene ID‑18329
SwissProt-1P0C0S8;P16104
Organism-2Mouse
Gene ID‑2319164
SwissProt-2P22752
Organism-3Rat
Gene ID‑3
SwissProt-3P02262
Organism-4
Gene ID‑4
SwissProt-4
Cellular LocalizationNucleus. Chromosome.
Unnamed: 38
Unnamed: 39
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