U-Blot® Histone H2A (Ubiquityl Lys119) Rabbit mAb
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Price range: $288.00 through $368.00
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H2A |
| Reactivity | Human,Mouse,Rat |
| Application | WB,IHC,IF,IP,ELISA,ChIP,Cut&Tag |
| MW(Calculated) | 14kD |
| MW(Observed) | 23kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate | Unconjugated |
| Modification | Ubiquityl |
| Modification site | Lys119 |
| Recommended dilution ratio | IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;ChIP 1:50-1:100;Cut&Tag 1:50-1:100; |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification | Protein A |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Recombinant Monoclonal |
| Clone Number | WT-176 |
| Immunogen | |
| Sequence | |
| Specificity | Endogenous |
| Gene name | HIST1H2AG H2AFP; HIST1H2AI H2AFC; HIST1H2AK H2AFD; HIST1H2AL H2AFI; HIST1H2AM H2AFN |
| Protein name | Histone H2A |
| Alternative name | Histone H2A type 1;H2A.1;Histone H2A/p; |
| Organism-1 | Human |
| Gene ID‑1 | 8329 |
| SwissProt-1 | P0C0S8;P04908;P20671;Q96KK5;Q6FI13;Q7L7L0 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319164 |
| SwissProt-2 | P22752 |
| Organism-3 | Rat |
| Gene ID‑3 | |
| SwissProt-3 | P02262 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus. Chromosome. |
| Unnamed: 38 | |
| Unnamed: 39 |
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