U-Blot® Histone H2B (Acetyl Lys21) Rabbit pAb

Price range: $288.00 through $368.00

SKU: WP0326-100
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Product details

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],

Specifications

TargetHistone H2B
ReactivityHuman,Rat,Mouse
ApplicationWB,ELISA
MW(Calculated)
MW(Observed)15kD
Host SpeciesRabbit
IsotypeIgG
ConjugateUnconjugated
ModificationAcetyl
Modification siteLys21
Recommended dilution ratioWB 1:500-2000;ELISA 1:10000-20000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthetic Acetyl peptide from human protein at AA range: 21
Sequence
SpecificityThe antibody detects endogenous Histone H2B when Acetyl occurs at Lys21
Gene nameHistone H2B
Protein nameHistone H2B
Alternative nameH2BFS;Histone H2B type F-S;Histone H2B.s;H2B/s;H2BK21AC
Organism-1Human
Gene ID‑1255626;3018;3017;8339;8343;8344;8346;8347
SwissProt-1Q96A08;P33778;P62807
Organism-2Mouse
Gene ID‑2319177;319178;319179
SwissProt-2
Organism-3Rat
Gene ID‑324829
SwissProt-3Q00729
Organism-4
Gene ID‑4
SwissProt-4
Cellular LocalizationNucleus . Chromosome .
Unnamed: 38
Unnamed: 39
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