U-Blot® Histone H2B (Acetyl Lys21) Rabbit pAb
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Price range: $288.00 through $368.00
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H2B |
| Reactivity | Human,Rat,Mouse |
| Application | WB,ELISA |
| MW(Calculated) | |
| MW(Observed) | 15kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Acetyl |
| Modification site | Lys21 |
| Recommended dilution ratio | WB 1:500-2000;ELISA 1:10000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic Acetyl peptide from human protein at AA range: 21 |
| Sequence | |
| Specificity | The antibody detects endogenous Histone H2B when Acetyl occurs at Lys21 |
| Gene name | Histone H2B |
| Protein name | Histone H2B |
| Alternative name | H2BFS;Histone H2B type F-S;Histone H2B.s;H2B/s;H2BK21AC |
| Organism-1 | Human |
| Gene ID‑1 | 255626;3018;3017;8339;8343;8344;8346;8347 |
| SwissProt-1 | Q96A08;P33778;P62807 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319177;319178;319179 |
| SwissProt-2 | |
| Organism-3 | Rat |
| Gene ID‑3 | 24829 |
| SwissProt-3 | Q00729 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus . Chromosome . |
| Unnamed: 38 | |
| Unnamed: 39 |
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