U-Blot® Histone H2B (Di Methyl Lys43) Rabbit pAb
Product details
Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],
Specifications
| Target | Histone H2B |
| Reactivity | Human,Mouse,Rat |
| Application | WB |
| MW(Calculated) | |
| MW(Observed) | 14kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Modification | Di Methyl |
| Modification site | Lys43 |
| Recommended dilution ratio | WB 1:500-1000 |
| Formulation | PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic Peptide of Histone H2B (Di Methyl Lys43) |
| Sequence | |
| Specificity | The antibody detects endogenous Histone H2B (Di Methyl Lys43) protein. |
| Gene name | HIST1H2BC |
| Protein name | Histone H2B type 1-A/Histone H2B type 1-B/Histone H2B type 1-C/E/F/G/I |
| Alternative name | H2BK43ME2;HIST1H2BA;TSH2B;Histone H2B type 1-A;Histone H2B, testis;Testis-specific histone H2B;HIST1H2BB;H2BFF;Histone H2B type 1-B;Histone H2B.1;Histone H2B.f;H2B/f;HIST1H2BC;H2BFL;HIST1H2BE;H2BFH;HIST1H2BF;H2BFG;HIST1H2BG;H2BFA;HIST1H2BI;H2BFK;Histone H2B type 1-C/E/F/G/I;Histone H2B.1 A;Histone H2B.a;H2B/a;Histone H2B.g;H2B/g;Histone H2B.h;H2B/h;Histone H2B.k;H2B/k;Histone H2B.l;H2B/l |
| Organism-1 | Human |
| Gene ID‑1 | 255626;3018;3017;8339;8343;8344;8346;8347 |
| SwissProt-1 | Q96A08;P33778;P62807 |
| Organism-2 | Mouse |
| Gene ID‑2 | 319177;319178;319179 |
| SwissProt-2 | |
| Organism-3 | Rat |
| Gene ID‑3 | 24829 |
| SwissProt-3 | Q00729 |
| Organism-4 | |
| Gene ID‑4 | |
| SwissProt-4 | |
| Cellular Localization | Nucleus . Chromosome . |
| Unnamed: 38 | |
| Unnamed: 39 |
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