SKU: WM0496 Categories: ,

HLX1 Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0496-50
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Product details

Background:
function:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis., sequence caution:Translation N-terminally extended., similarity:Belongs to the H2.0 homeobox family., similarity:Contains 1 homeobox DNA-binding domain., tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,

Specifications

Size50μL/100μL
TargetHLX1
ReactivityHuman, Mouse, Rat, Bovine, Dog, Pig
ApplicationsWB
MW(Calculated)51kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:1000-1:2000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationAffinity purification
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number17E8
ImmunogenPurified recombinant human HLX1 (C-terminus) protein fragments expressed in E.coli.
SpecificityHLX1 Monoclonal Antibody detects endogenous levels of HLX1 protein.
Gene NameHLX
Protein NameH2.0-like homeobox protein
Other NameHLX; / HLX1; / H2.0-like homeobox protein; / Homeobox protein HB24; / Homeobox protein HLX1
SpeciesHuman
Gene ID3142
UniprotQ14774,
Species.1Mouse
Gene ID.115284
Uniprot.1Q61670,
Species.2Rat
Gene ID.2364069
Uniprot.2A0JPN1
Cellular LocalizationNucleus .
Tissue ExpressionLow level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.
Signaling_pathway
Research Areas
FunctionFunction:Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis.,sequence Caution:Translation N-terminally extended.,similarity:Belongs to the H2.0 homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Low level in normal B and T-cells, high level in activated lymphocytes and monocytes. Also found in thymus, tonsil, bone marrow, developing vessels, and fetal brain.,
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