hnRNP G Polyclonal Antibody
Ucallm_WP12719-50
Price range: $268.00 through $328.00
Product details
Background:
This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009],
Specifications
| Size | 50μL/100μL |
| Target | hnRNP G |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 40kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human hnRNP G. AA range:6-55 |
| Specificity | hnRNP G Polyclonal Antibody detects endogenous levels of hnRNP G protein. |
| Gene Name | RBMX |
| Protein Name | RNA-binding motif protein X chromosome |
| Other Name | RBMX; / HNRPG; / RBMXP1; / RNA-binding motif protein; / X chromosome; / Glycoprotein p43; / Heterogeneous nuclear ribonucleoprotein G; / hnRNP G |
| Species | Human |
| Gene ID | 27316 |
| Uniprot | P38159, |
| Species.1 | Mouse |
| Gene ID.1 | 19655 |
| Uniprot.1 | Q9WV02, |
| Species.2 | Rat |
| Gene ID.2 | 302855 |
| Uniprot.2 | Q4V898 |
| Cellular Localization | Nucleus . Component of ribonucleosomes. Localizes in numerous small granules in the nucleus. |
| Tissue Expression | Expressed strongly in oral keratinocytes, but only weakly detected in oral squamous cell carcinomas (at protein level). |
| Signaling_pathway | |
| Research Areas | >>Spliceosome |
| Function | Function:RNA-binding protein which may be involved in pre-mRNA splicing.,PTM:Arg-185 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Cleavage of initiator Met is partial. If Met-1 is not removed, it is acetylated. If it is removed, Val-2 is acetylated.,PTM:O-glycosylated.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Component of ribonucleosomes.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8. Interacts with KHDRBS3., |
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