Price range: $268.00 through $328.00
Background:
heterogeneous nuclear ribonucleoprotein L like(HNRNPLL) Homo sapiens HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],
| Size | 50μL/100μL |
| Target | hnRNP LL |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HNRPLL. AA range:241-290 |
| Specificity | hnRNP LL Polyclonal Antibody detects endogenous levels of hnRNP LL protein. |
| Gene Name | HNRPLL |
| Protein Name | Heterogeneous nuclear ribonucleoprotein L-like |
| Other Name | HNRPLL; / SRRF; / BLOCK24; / Heterogeneous nuclear ribonucleoprotein L-like; / hnRNPLL; / Stromal RNA-regulating factor |
| Species | Human |
| Gene ID | 92906 |
| Uniprot | Q8WVV9, |
| Species.1 | Mouse |
| Gene ID.1 | 72692 |
| Uniprot.1 | Q921F4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | nucleus,membrane,viral nucleocapsid,intracellular ribonucleoprotein complex, |
| Tissue Expression | Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May bind RNA and play a role in mRNA processing.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung., |
