Price range: $268.00 through $328.00
Background:
This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],
| Size | 50μL/100μL |
| Target | HORMAD1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 45kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HORMAD1. AA range:321-370 |
| Specificity | HORMAD1 Polyclonal Antibody detects endogenous levels of HORMAD1 protein. |
| Gene Name | HORMAD1 |
| Protein Name | HORMA domain-containing protein 1 |
| Other Name | HORMAD1; / NOHMA; / HORMA domain-containing protein 1; / Cancer/testis antigen 46; / CT46; / Newborn ovary HORMA protein |
| Species | Human |
| Gene ID | 84072 |
| Uniprot | Q86X24, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q9D5T7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Chromosome . Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). . |
| Tissue Expression | Testis-specific. Over-expressed in carcinomas. |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 HORMA domain.,tissue specificity:Testis-specific. Over-expressed in carcinomas., |
