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Home/Reagents/Antibody/Primary antibody/Polyclonal Antibody/Rabbit pAb/Hox-A1/B1/D1 Polyclonal Antibody
SKU: WP12728 Categories: ,

Hox-A1/B1/D1 Polyclonal Antibody

Ucallm_WP12728-50

Price range: $268.00 through $328.00

SKU: WP12728-100
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Product details

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetHox-A1/B1/D1
ReactivityHuman, Mouse
ApplicationsIHC, IF, ELISA
MW(Calculated)32kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human HOXA1/B1/D1. AA range:216-265
SpecificityHox-A1/B1/D1 Polyclonal Antibody detects endogenous levels of Hox-A1/B1/D1 protein.
Gene NameHOXB1
Protein NameHomeobox protein Hox-B1
Other NameHOXB1; / HOX2I; / Homeobox protein Hox-B1; / Homeobox protein Hox-2I; / HOXA1; / HOX1F; / Homeobox protein Hox-A1; / Homeobox protein Hox-1F; / HOXD1; / HOX4; / HOX4G; / Homeobox protein Hox-D1; / Homeobox protein Hox-GG
SpeciesHuman
Gene ID3211;3198;3231
UniprotP14653;P49639;Q9GZZ0,
Species.1Mouse
Gene ID.115407
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus.
Tissue ExpressionPCR rescued clones,
Signaling_pathwayCellular Processes >> Cellular community - eukaryotes >> Signaling pathways regulating pluripotency of stem cells
Research Areas>>Signaling pathways regulating pluripotency of stem cells
FunctionFunction:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.,polymorphism:The two common alleles; HOX1B*A and HOX1B*B have a frequency of 78.8% and 21.2% respectively.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
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