SKU: WP12736 Categories: ,

Hox-B9 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP12736-100
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Product details

Background:

This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetHox-B9
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)28kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human HOXB9. AA range:201-250
SpecificityHox-B9 Polyclonal Antibody detects endogenous levels of Hox-B9 protein.
Gene NameHOXB9
Protein NameHomeobox protein Hox-B9
Other NameHOXB9; / HOX2E; / Homeobox protein Hox-B9; / Homeobox protein Hox-2.5; / Homeobox protein Hox-2E
SpeciesHuman
Gene ID3219
UniprotP17482,
Species.1Mouse
Gene ID.115417
Uniprot.1P20615
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus.
Tissue ExpressionMuscle,Placenta,
Signaling_pathway
Research Areas
Functiondevelopmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,Function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Abd-B homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
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