SKU: WP0633 Categories: ,

HSP72 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0633-100
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Product details

Background:

function:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage., similarity:Belongs to the heat shock protein 70 family., subunit:Interacts with ZNF541.,

Specifications

Size50μL/100μL
TargetHSP72
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)70kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 470-550
SpecificityHSP72 Polyclonal Antibody detects endogenous levels of protein.
Gene NameHSPA2
Protein NameHeat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2)
Other Name
SpeciesHuman
Gene ID3306
UniprotP54652,
Species.1Mouse
Gene ID.1
Uniprot.1P17156,
Species.2Rat
Gene ID.2
Uniprot.2P14659
Cellular LocalizationCytoplasm, cytoskeleton, spindle . Colocalizes with SHCBP1L at spindle during the meiosis process. .
Tissue ExpressionBrain,Eye,Lung,
Signaling_pathwayOrganismal Systems >> Immune system >> Antigen processing and presentation
Research Areas>>Spliceosome; / >>MAPK signaling pathway; / >>Protein processing in endoplasmic reticulum; / >>Endocytosis; / >>Longevity regulating pathway - multiple species; / >>Antigen processing and presentation; / >>Estrogen signaling pathway; / >>Prion disease; / >>Legionellosis; / >>Toxoplasmosis; / >>Measles; / >>Lipid and atherosclerosis
FunctionFunction:In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.,similarity:Belongs to the heat shock protein 70 family.,subunit:Interacts with ZNF541.,
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