Price range: $268.00 through $328.00
Background:
ELAV like RNA binding protein 2(ELAVL2) Homo sapiens The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
| Size | 50μL/100μL |
| Target | HuB/D |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 40kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ELAV2/4. AA range:61-110 |
| Specificity | HuB/D Polyclonal Antibody detects endogenous levels of HuB/D protein. |
| Gene Name | ELAVL2/ELAVL4 |
| Protein Name | ELAV-like protein 2/ELAV-like protein 4 |
| Other Name | ELAVL2; / HUB; / ELAV-like protein 2; / ELAV-like neuronal protein 1; / Hu-antigen B; / HuB; / Nervous system-specific RNA-binding protein Hel-N1; / ELAVL4; / HUD; / PNEM; / ELAV-like protein 4; / Hu-antigen D; / HuD; / Paraneoplastic encephalomyelitis antigen HuD |
| Species | Human |
| Gene ID | 1993;1996 |
| Uniprot | Q12926;P26378, |
| Species.1 | Mouse |
| Gene ID.1 | 15569;15572, |
| Uniprot.1 | |
| Species.2 | Rat |
| Gene ID.2 | 432358 |
| Uniprot.2 | Q8CH84;O09032 |
| Cellular Localization | nucleoplasm, |
| Tissue Expression | Brain; neural-specific. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.,similarity:Belongs to the RRM elav family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Brain; neural-specific., |
