SKU: WP2564 Categories: ,

Iba1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2564-100
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Product details

Background:

This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],

Specifications

TargetAIF1
ReactivityHuman, Rat, Mouse
ApplicationsWB, IF, ELISA
MW(Calculated)
MW(Observed)16kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000;ELISA 1:5000;IF 1:100-300;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
Sequence
SpecificityAIF1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameAIF1 G1 IBA1
Protein NameAllograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
Alias
Organism-1Human
Gene ID-1199
SwissProt-1P55008
Organism-2Mouse
Gene ID-2
SwissProt-2O70200
Organism-3Rat
Gene ID-3
SwissProt-3P55009
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .
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